The most robust evidence of association with ADHD has been shown for dopamine receptors DRD4 and DRD5 variants, for dopamine transporters gene DAT1 (SLC6A3) regulating the reuptake of dopamine in the presynaptic cleft [94], and for synaptosomal protein SNAP-25 [95]. The gene discussed is SLC6A3; the disease is attention deficit-hyperactivity disorder.