The imputed regulatory role for SOX9 fits with the pancreatic hypoplasia observed in campomelic dysplasia (Piper et al., 2002) and the pancreatic enrichment of WNT, NOTCH, and BMP signaling pathways, which are known to regulate SOX9 (Figure 2C; Pritchett et al., 2011). This evidence concerns the gene SOX9 and campomelic dysplasia.