To this end, we subcutaneously injected into immunodeficient NOD‐scid IL2Rgammanull (NSG) mice ptch1/p53 double‐deficient murine BCC cells expressing readily detectable levels of Hdac1/2/3 in a Hh/Gli independent manner as assessed by vismodegib treatment (Supporting Information, Fig. 7). Here, HDAC1 is linked to skin basal cell carcinoma.