The tumour‐suppressive function of SMCT1 is based on its ability to transport pyruvic acid, an inhibitor of histone deacetylases, into cells in non‐colonic tissues [522]; in the colon, the ability of SMCT1 to transport butyric acid and propanoic acid, also inhibitors of histone deacetylases, underlies the tumour‐suppressive function of this transporter [195, 196, 233]. This evidence concerns the gene SLC5A8 and neoplasm.