ALDH7A1 and pyridoxine-dependent epilepsy: Pyridoxine dependent epilepsy (PDE) (OMIM#266100) caused by likely pathogenic variants in ALDH7A1 (PDE-ALDH7A1) (GenBank accession nos: GI319655560 GI320202963 and GI319655559) is an autosomal recessively inherited neurometabolic disease [1,2].