This occurs hypothetically because of the altered homing of clonal CD117+ PCs that are redirected towards the neutrophil precursor niches, thus giving space for maintenance of residual nPCs.39, 40 Conversely, adverse prognosis is associated with expression of CD28 (T-cell co-stimulatory receptor) that is positive in approximately 35% of MM cases. Here, KIT is linked to Miyoshi myopathy.