MYD88 and Miyoshi myopathy: This suggests that the PC compartment is enriched in more immature clonal PCs with the plasmablastic phenotype.103 The different antigenic profile of clonal PCs can have a valuable input to distinguish WM from IgM MM, together with the MYD88 mutation status (not present in IgM MM) and the presence of t(11; 14) (does not occur in WM but with a high incidence in IgM MM).93, 104, 105