Towards this we took advantage of the TCGA pan-cancer expression data set (Akbani et al., 2014; Weinstein et al., 2013) and evaluated Daam2 expression across a spectrum of 34 malignancies, finding that it’s most highly expressed in low-grade glioma (LGG) and glioblastoma multiforme (GBM) (Figure 1A). Here, DAAM2 is linked to central nervous system cancer.