Using an electrochemiluminescent assay, O’Shaunessy et al. [36] showed that as a single biomarker, FRα was able to discriminate between ovarian cancer and normal serum samples, with AUCs ranging from 0.62 for stage I samples to 0.94 and 0.92 for stage III and IV samples [36]. The gene discussed is FOLR1; the disease is ovarian cancer.