Finally, subjects with the T allele of SMAD2 rs11082639 and the G allele of TGFBR2 rs3773651 had a 1.55-fold higher risk of MetS than those with the T allele of SMAD2 rs11082639 and the AA genotype of TGFBR2 rs3773651 (Table 5). Here, TGFBR2 is linked to metabolic syndrome.