IGHE and allergic disease: In another study that measured markers for allergy and inflammatory processes in human cord blood and compared the amount of maternal urinary BPA concentration during the first trimester, it was found that thymic stromal lymphopoietin (TSLP), IL-33 and IgE levels were elevated in a non-linear manner in both males and females exposed to BPA during fetal development, suggesting that both low and high exposure levels of BPA during the first trimester might result in allergies or inflammatory diseases [68].