Whereas, expression of PD-1 (p = 0.069), PD-1+PD-L1+ (p = 0.058), PD-1+CD8+ (p = 0.069) and PD-1+PD-L1+CD8+ (p = 0.058) showed a trend towards better MFS in osteosarcoma (Figure 3G–3H). The gene discussed is CD274; the disease is osteosarcoma.