EGFR and non-small cell lung carcinoma: The preliminary data on osimertinib as first-line treatment in EGFR mutated treatment naïve NSCLC patients showed median progression free survival of 19.3 months (95% CI, 13.7, Not Calculable) with disease control rate of 97% (95% CI 88.5–99.6) and progression free survival in 55% of patients at 18 months with manageable safety profile [100].