In humans, equivalent BAFT3 dependent DCs are identified by the expression of CD11c, CLEC9A, XCR1 and CD141 [22], have been found in different tumor types and, just as the murine DC, seem to be relevant in anti-tumor responses, since their presence correlates with a superior outcome in melanoma patients [14, 23]. Here, XCR1 is linked to neoplasm.