De Summa et al. [74] show that overexpression of miR-17 in both mesenchymal-like BRCA1-proficient and in BRCA1- and BRCA2-mutated BC cell lines in addition to the significant overexpression of miR-17 in sporadic patients seems to suggest that downregulation of BRCA1, a presumed target of miR-17-5p mimics a ‘BRCAness’ phenotype, that is, a phenotype that some sporadic cancers share with BRCA1- or BRCA2-mutation carriers. The gene discussed is BRCA2; the disease is breast cancer.