The 17 flapped DEGs are: SOCS3, Cc19, MMP14, Igf1, Aox3, C1qa, C1qb, C3ar1, Cc112, Cc12, Cc18, Cc19, Cxc110, Fcgr1, Gsta2, Kng1 and Pdgfc. Then, we tested changes in mRNA level using the method of RT-PCR based on the BLM-induced pulmonary fibrosis model that we built by ourselves. The gene discussed is KNG1; the disease is pulmonary fibrosis.