CCND1 and cancer: The expression levels of cell cycle proteins MMP7, C-myc, C-jun, CYCLIND1 and β-catenin degradation protein GSK-3β in the Wnt/β-catenin signaling pathway were higher in cancer than in non-cancer tissues in all the wild type and the homozygous and heterozygous variations of the patients (Figure 2A, 2G and Figure 3A, 3B, 3C, 3D, 3E).