As reduced doxo resistance in CD44+/CD24- breast cancer cells is evidenced by suppression of CD44 [42], we analyzed mRNA and protein levels for CD44; the result reveals MCF7/ADR cells with ∼150- and 16-fold higher levels of mRNA and protein, respectively, than in MCF7 (Figure 1F and 1G). The gene discussed is CD44; the disease is breast cancer.