To verify the in vivo effects of NEAT on nasopharyngeal carcinoma xenograft models, CNE2 cells with OE-NEAT1, OE-NEAT1+miRNA-101-3p or Sh-NEAT1 were subcutaneously injected into nude mice, and the xenograft tumor received 4 Gy irradiation at days 1, 5, 9 and 13. The gene discussed is NEAT1; the disease is nasopharyngeal carcinoma.