Moreover, some lncRNAs could regulate metastasis and/or irradiation-resistance in NPC, e.g., MALAT1, AFAP1-AS1, LINC01420, ROR and HNF1A-AS have been reported to promote the proliferation and metastasis of NPC cells, but LINC0086 is negatively related to the tumor size and metastasis of NPC [21, 22, 32, 34, 35, 45-48]. The gene discussed is MALAT1; the disease is nasopharyngeal carcinoma.