It’s shown that EBV can encode some viral oncoproteins that involved in EBV tumorigenicity (including EBNA1, EBNA2, LMP1, LMP2, EBNA3A, EBNA3C, BARF0, BALF1, RPMS1, BARF1 and BNLF1) [27–38], which are associated with Burkitt’s lymphoma (EBNA1, LMP2A and BARF0), Hodgkin’s disease, nasopharyngeal carcinoma and NK/T-cell lymphoma (EBNA1, LMP1, LMP2A and LMP2B), gastric carcinomas (BARF1), post-transplant lymphoproliferative disorders and AIDS-related lymphomas (EBNA1, EBNA3A, LMP1, LMP2A and LMP2B). Here, PSMB9 is linked to lymphoproliferative syndrome.