ELF3 and breast carcinoma: Since the ESE-1 gene locus maps to chromosome 1q31.1, a region that is often amplified in breast cancer [16, 23], we first investigated ESE-1 copy number level between normal breast tissue and breast carcinoma subtypes using DNA data available from the TCGA Breast 2 cohort (generated by the TCGA Research Network: http://cancergenome.nih.gov/) in Oncomine [24].