Our results also revealed numerous proteins that have not been associated with or reported in BC tissue, including PGRMC1, FUCA1, BROX, coatomer protein complex subunit alpha (COPA), or threonyl-TRNA synthetase (TARS), with the differential expression of FUCA1, BROX, PGRMC1, and PSMD12 having been further confirmed in a small set of additional tumors by IHC. This evidence concerns the gene COPA and breast cancer.