The top-ranked proteins were: elevated sBAFF and downregulated REG4, sPECAM1, sIL6R, sPDGFB, midkine, sHGF, TGFB1, sAREG, and sMICA in MM-ASCT comparing to MM (Table 1D, Figure 3). The gene discussed is MDK; the disease is Miyoshi myopathy.