KDR and colorectal carcinoma: For case 3, where only the CRC culture was sequenced, missense somatic mutations were present in the CDKN2A, KDR, KIT Proto-Oncogene, Receptor Tyrosine Kinase (KIT), JAK3, MET Proto-Oncogene, Receptor Tyrosine Kinase (MET) and TP53 genes.