CCND1 and colorectal carcinoma: We also found that compared with GG homozygote, AA homozygote, or AG heterozygote of the CCND1 G870A polymorphism was significantly associated with a higher overall risk for CRC (AA vs GG: OR = 1.28, 95% CI = 1.10–1.49; AG vs GG: OR = 1.15, 95% CI = 1.06–1.25).