CCND1 and colorectal carcinoma: As for the study design, we found a significant association in HB studies, but not in PB or FB studies, which was consistent with a previous meta-analysis.[24] When stratified by type of CRC, no relationship was identified between the CCND1 G870A polymorphism and the risk of CRC in subsets of patients with either sCRC or HNPCC.