HDAC6 and Abnormal retinal morphology: It is involved in a variety of cellular events, including proteasome dysfunction, cell adhesion regulation, heat-shock responses and redox regulation.21, 23, 24, 37 The overexpression of HDAC6 has been connected to neurodegenerative disorders, and its specific suppression may provide protection.38, 39 Here we show that HDAC6 is constitutively expressed in the murine retina and may play a role in retinal diseases, which involve oxidative damage and photoreceptor cell death.