The fibroblast growth factor 1 (FGF1) is an oncogene, which regulates many cellular processes including cell proliferation, differentiation and survival.1, 2, 3 FGF1 has been linked to tumor development, as it is upregulated in various cancers (breast, ovarian, gliomas and astrocytomas). The gene discussed is FGF1; the disease is glioma.