For example, Th17 immune response against Klebsiella pneumonia, mediated by IL-17A and IL-22 includes the induction of CXCL1, CXCL2, CXCL5 causing neutrophil infiltration and the production of lipocalin-2 (LCN2), an enzyme subsequently restricting bacterial growth by preventing access to dietary iron [37]. The gene discussed is LCN2; the disease is Klebsiella pneumonia.