The transporters ZNT5 and ZNT7 are also relatively highly expressed in pancreatic β-cells, [61,116,117], and both may be associated with β-cell function: loss-of-function of Znt5 is associated with attenuation of the incidence of diabetes and mortality [103], whereas loss-of-function of Znt7 impairs glucose tolerance and reduces glucose-stimulated increases in plasma insulin levels, hepatic glycogen levels, and pancreatic insulin content [104,105,118]. This evidence concerns the gene SLC30A7 and diabetes mellitus.