We crossed our BCCIP-CKD (LoxPshBCCIP;K14-Cre) mice with mice carrying floxed Trp53 alleles (Trp53flox/flox), producing four different genotypes: LoxPshBCCIP+:Trp53flox/flox, LoxPshBCCIP+:Trp53flox/wt, Trp53flox/flox, and Trp53flox/wt (all with K14-Cre). The gene discussed is KRT14; the disease is chronic kidney disease.