For example, lncRNA FTX is down‐regulated in HCC tissues, and it could inhibit HCC cells invasion and proliferation by repressing Wnt/β‐catenin signaling activity and impeding DNA replication through competitively sponging miR‐374a and binding to the DNA replication licensing factor MCM2 17. This evidence concerns the gene MCM2 and hepatocellular carcinoma.