This proposal stratifies gastric adenocarcinomas into tumours with MSI, microsatellite-stable tumours showing epithelial to mesenchymal transition (MSS/EMT), MSS tumours with intact TP53 activity (MSS/TP53+) and MSS tumours with functional loss of TP53 (MSS/TP53−) [4]. Here, TP53 is linked to gastric adenocarcinoma.