In a previous work from our group, we have analyzed the miRNA transcriptome of two different colorectal carcinoma (CRC) cell lines and their secreted exosomes before and after treatment with Cetuximab, a monoclonal antibody that binds and blocks the Epidermal Growth Factor Receptor (EGFR; Ragusa et al., 2014, 2015b). Here, EGFR is linked to colorectal carcinoma.