Notably, cg04983687 in the ZFPM1 gene, which was the top hit in the cross-sectional model of current asthma at 7.5 years, remained nominally associated in both longitudinal models (P = 0.008 for current asthma at 7.5 years and methylation in adolescence, and P = 0.01 for current asthma at 16.5 years and methylation childhood) with the same direction of effect. Here, ZFPM1 is linked to asthma.