WWC1 and nonpapillary renal cell carcinoma: Bisulfite sequencing and dichotomous analysis revealed that KIBRA CpG methylation occurred significantly more often in ccRCC samples (methylation level 73/504 [14.5%]) compared to control samples (methylation level 76/1008 [7.5%]; p = 0.0001, OR = 1.921, [CI 95%] = 1.369–2.695).