In the light of altered plasma GLP-1 in diabetes, the reduced prevalence of aneurysm in diabetic patient groups, and indicated protective effects of GLP-1 analogues in models of aortic aneurysm, plasma GLP-1 may not only be identified as a risk factor for aneurysm formation in high-risk patients, but stable GLP-1 analogues currently used in diabetes therapy may be indicated for patients with increased risk of aortic aneurysm. Here, GCG is linked to aneurysm.