In contrast with our previous study [13] that majority of cagA genotype in strains isolated from Thai in Bangkok (capital city) was Western-type, Thai strains in Maesot contained East-Asian-type cagA. It is indicated that generally Thai in Maesot had higher risk for gastric cancer than Thai who living in the capital that may also partly explained the difference of gastric cancer risk between two regions (ASR female and male in North vs Central were 4.1, 5.4 vs. 1.8, 3.8, respectively) [55]. The gene discussed is S100A8; the disease is gastric cancer.