MTOR and central nervous system cancer: For the highest expressing miRNA, hsa-miR-451a (Table 3), DIANA analysis indicated brain related cluster enrichment for Parkinson’s disease (2 genes, p = 1.0-5) and glioma (3 genes, p = 0.02), and clusters for signaling pathways related to aging, including mTOR signaling (6 genes, p = 0.002) and AMPK signaling (6 genes, p = 0.027).