No significant expression level changes were observed at RNA level for other genes causing adrenal insufficiencies in humans (Aaas, Abcd1, Aire, Cdkn1c, Cyp11a1, Cyp11b1, Cyp17a1, Cyp21a1, Mcm4, Nr5a1, Por and Txnrd2). The gene discussed is TXNRD2; the disease is Adrenal insufficiency.