Similarly, “mild” mutations in the cholesterol side chain cleavage enzyme (CYP11A1, the first enzyme in the steroid pathway), can give rise to FGD (Rubtsov et al. 2009, Parajes et al. 2011, Sahakitrungruang et al. 2011). Here, CYP11A1 is linked to Aarskog-Scott syndrome, X-linked.