Furthermore, in 50 patients who were at risk for AKI and were undergoing cardiacsurgery with cardiopulmonary bypass, Meersch et al.(84) investigated whether urinary TIMP-2*IGFBP7could predict renal recovery from AKI, which was defined as a plasma creatininevalue at hospital discharge equal or lower than that at baseline. Here, TIMP2 is linked to acute kidney injury.