URGCP and central nervous system cancer: The data presented in this report suggests a pivotal role of URGCP in glioma growth, first, URGCP was found to be overexpressed in glioma cell lines, and in a large proportion of clinical glioma samples; second, the expression levels of URGCP correlated with the pathological grades and the overall survival time of glioma patients; third, silencing URGCP suppressed the proliferative activity of glioma in vivo and in vitro.