Among these hair development-related genes, the key transcription regulators were significantly enriched in the periodic DEG genes, such as HOXC13, MSX1, DLX1, ELF5, DLX4, DLX3, MSX2, and FOXN1. Many of these genes are known crucial factors during HF cycling in humans and mice. This evidence concerns the gene MSX2 and hydrops fetalis.