INS and diabetes mellitus: National diabetes reports from other countries indicate largely consistent contemporary prevalence of 15% and 19% for insulin monotherapy and combination therapy with concomitant oral glucose-lowering medicines, respectively, among people with T2D in the United Kingdom Clinical Practice Research Datalink21 and the frequency of 26% for insulin use among people with diabetes as reported in the Center for Disease Control and Prevention 2011 US National Diabetes Fact Sheet22.