In this regard, patients with RA had lower levels of total cholesterol (206 ± 36 vs. 219 ± 37 mg/dl, p = 0.000), LDL cholesterol (121 ± 31 vs. 135 ± 34 mg/dl, p = 0.000), HDL cholesterol (56 ± 15 vs. 63 ± 18 mg/dl, p = 0.000), and apolipoprotein A1 (170 ± 28 vs. 191 ± 35 mg/dl, p = 0.000). The gene discussed is APOA1; the disease is rheumatoid arthritis.