Transgenic mice overexpressing integrin beta 1 (Itgb1) in the suprabasal layer of the epidermis (Tg(Itgb1)0869Fmw) exhibit epidermal hyperproliferation, perturbed keratinocyte differentiation and skin inflammation [24], which resembles the Sharpincpdm/cpdm phenotype. This evidence concerns the gene ITGB1 and dermatitis.