In a mouse model of experimental TB, no changes in serum insulin levels were observed upon infection (uninfected: 1.70 ± 0.46 ng/ml; Mtb: 4.14 ± 2.94 ng/ml; data representative of 3 independent experiments; 4 to 5 animals per group) indicating that CD8+ T cells do not induce insulin resistance. This evidence concerns the gene CD8A and tuberculosis.