DYNC1H1, which was associated with the 46 traits (p-value ≤ 3.46 × 10−58), HOMA-IR (p-value ≤ 4.76 × 10−108), insulin (p-value ≤ 2.83 × 10−28), glucose (p-value ≤ 1.07 × 10−10) and creatinine (p-value ≤ 2.57 × 10−9), has been associated with hyperinsulinemia, hyperglycemia, the progress of glucose intolerance [74], and the blood creatinine level [75]. This evidence concerns the gene INS and hyperinsulinism.