NR4A1 and invasive breast carcinoma: Hormone receptor negative invasive breast cancer cases were most likely to have distant recurrence in the first 5 years post initial diagnosis (88%) [median DFI = 2.6 years] while hormone receptor positive rMBC cases had longer time to distant recurrence with half before and half after 5 years post initial diagnosis [median DFI = 5.0 years] (p < 0.001).