Moreover, DNA methylation is maintained on subsequent cells by DNMT1, responsible for reproducing the parent strand's methylation pattern in the daughter strand [8], and mutations in the DNMT family are frequently described in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) [17–19], correlating with poor prognosis [20]. This evidence concerns the gene DNMT1 and myelodysplastic syndrome.