These findings suggest that Zdhhc13-mediated Drp1 modifications may be also dependent on the presence of brain-specific interacting proteins required for mitophagy, fusion-fission processes, or protection of mitochondrial function62 with more overt mitochondrial deficits in those brain regions with critical roles in the circuitry of anxiety [cortex, amygdala, hippocampus, and striatum32], other than those tested here. Here, ZDHHC13 is linked to Anxiety.