Absence of gastric acid exacerbated NASH (Atp4aSl/Sl vs. WT mice), demonstrated by increased liver to body weight ratio (Fig. 3a), levels of ALT (Fig. 3b), steatosis (Fig. 3c–e), inflammation (Fig. 3f, g), and fibrosis (Fig. 3h–j). Here, GPT is linked to metabolic dysfunction-associated steatohepatitis.