Absence of gastric acid exacerbated NASH (Atp4aSl/Sl vs. WT mice), demonstrated by increased liver to body weight ratio (Fig. 3a), levels of ALT (Fig. 3b), steatosis (Fig. 3c–e), inflammation (Fig. 3f, g), and fibrosis (Fig. 3h–j). This evidence concerns the gene GPT and steatosis.